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The algorithm was designed to protect against accidental errors, such as a digit mistyping.

It will detect any single-digit error, as well as almost all transpositions of adjacent digits.

The Luhn algorithm was developed by German computer scientist Hans Peter Luhn in 1954.

It calculates simple checksum formula used to validate identification numbers such as credit card numbers.

Objective To develop and validate an updated version of the QFracture algorithm for estimating the risk of a patient sustaining an osteoporotic fracture or hip fracture in a primary care population.

Design Prospective open cohort study using routinely collected data from 420 general practices in the United Kingdom to develop updated QFracture scores and 207 practices to validate scores.

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An understanding of the prevalence and management of paediatric asthma is hindered by issues with disease definition and diagnosis.Using this “big data” method is much more complete; it is also cheaper and faster.Methods developed in this pilot project led directly to an additional publication examining the relationship between patient-sharing networks and the cost and intensity of medical care delivery and substantially informed other work in this area, including in a landmark paper in JAMA mapping the network of doctors in the entire USA, all among the first publications on physician patient-sharing networks in the field.Outcomes Incident diagnosis of osteoporotic fracture (vertebral, distal radius, proximal humerus, or hip) and incident hip fracture recorded in general practice records or linked cause of death records.Results We found significant independent associations with overall fracture risk in women for age, body mass index, ethnic origin, alcohol intake, smoking status, chronic obstructive pulmonary disease or asthma, any cancer, cardiovascular disease, dementia, diagnosis or treatment for epilepsy, history of falls, chronic liver disease, Parkinson’s disease, rheumatoid arthritis or systemic lupus erythematosus, chronic renal disease, type 1 diabetes, type 2 diabetes, previous fracture, endocrine disorders, gastrointestinal malabsorption, any antidepressants, corticosteroids, unopposed hormone replacement therapy, and parental history of osteoporosis.

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Returning by popular demand, Christopher Wright led us in worship last year and he will be joining us again this year.